Synonyms: Rp-8-Bromo-cGMPS sodium salt; Rp-8-Bromoguanosine- 3', 5'- cyclic monophosphorothioate sodium salt
Molecular Formula: C10H10BrN5O6PS · Na
Molecular Weight: 462.15
Linear Structural Formula: C10H10BrN5O6PS · Na
MDL Number: MFCD04037242
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). Rp-8-bromo-cGMPS is resistant to hydrolysis by phosphodiesterases and binds cGK without activating it, resulting in competitive inhibition.