ROCHE Tris base

Synonyms: Trizma^® base; amino-2-(hydroxymethyl)-1,3-propanediol, 2-; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; THAM; Tris base; Tris(hydroxymethyl)aminomethane; Trometamol

Empirical Formula (Hill Notation): C₄H₁₁NO₃

Formula Weight: 121.14

Linear Formula: NH₂C(CH₂OH)₃

MDL Number: MFCD00004679

Purity: ‚≥99.9% (titration)

Boiling Point: 219-220 °C/10 mmHg(lit.)

Melting Point: 167-172 °C (lit.)

Storage: 20-25°C

Beilstein Registry Number: 741883

UNSPSC Code: 12352200

RIDADR: NONH for all modes of transport

Other Notes:
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Quality:
Contaminants: <0.001% PK and aldolase, each, <0.01% GOT, GPT, MDH and myokinase, each

Legal Information:
Trizma is a registered trademark of Sigma-Aldrich Co. LLC