Purity: 95% (electrophoresis)
Specific Activity: ~8 units/mg protein (At 25 °C with Chromozym PL as the substrate.)
UNSPSC Code: 12352204
RIDADR: NONH for all modes of transport
Application:
Use Plasmin, human in coagulation research and medical research. It is used for protein structure analysis, sequence analysis, and biochemical research. The enzyme converts fibrin into soluble products.
Biochem/physiol Actions:
Plasmin is a direct acting fibrinolytic enzyme present in blood. Its activity is independent of plasminogen presence during fibrinolysis. Plasmin is rapidly and irreversibly inhibited by α-2 antiplasmin.
General description:
Inhibitors: DFP, PMSF, TLCK, leupeptin, aprotinin, soybean trypsin inhibitor, α1-antitrypsin, α2-macroglobulin, anti-thrombin III heparin, APMSF, and α2-antiplasmin
Other Notes:
For life science research only. Not for use in diagnostic procedures.
Physical form:
Suspension in 3.2 M ammonium sulfate solution
Preparation Note:
Stabilizers: Human plasmin does not contain stabilizers.
Storage conditions (working solution): 2 to 8 °C
Diluted solution (pH 8.6) is stable at 2 to 8 °C for at least 1–2 weeks. For storage of dialyzed solution freezing in aliquots is recommended.
Specificity:
Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin.