Synonyms: D-Glucose 6-phosphate disodium salt hydrate; G-6-P-Na2; Robison ester
Empirical Formula (Hill Notation): C6H11Na2O9P ¬? xH2O
Formula Weight: 304.10 (anhydrous basis)
Linear Formula: C6H11Na2O9P ¬? xH2O
MDL Number: MFCD00150940
Beilstein Registry Number: 5199009
UNSPSC Code: 12352200
RIDADR: NONH for all modes of transport
Application:
Substrate for glucose-6-phosphatase.
Biochem/physiol Actions:
In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.
General description:
Disodium salt
Other Notes:
For life science research only. Not for use in diagnostic procedures.
Quality:
Contaminants: <0.2% glucose (enzymatic)
Components:
77% glucose-6-P (enzymatic), 13% sodium, 8% water
Formula variant:
C6H11O9PNa2