Specific Activity: ~200 units/mg protein (At 25 °C with adenosine as the substrate.)
UNSPSC Code: 12352204
RIDADR: NONH for all modes of transport
Application:
Deamination of adenosine analogs to the corresponding inosine analogs.
Adenosine deaminase has been used to pre-treat primary Kupffer cells.
Biochem/physiol Actions:
Adenosine deaminase (ADA) is involved in the deamination of adenosine to inosine and 2′ deoxyadenosine to 2′-deoxyinosine.
General description:
Adenosine aminohydrolase.
Adenosine deaminase (ADA) is a zinc metalloenzyme.
Other Notes:
For life science research only. Not for use in diagnostic procedures.
Quality:
Contaminants: <0.01% alkaline phosphatase, AMP-deaminase, guanase, and nucleoside phosphorylase each
Physical form:
Solution in 50% glycerol (v/v), 10 mM potassium phosphate, pH approximately 6
Preparation Note:
Storage conditions (working solution): ADA (all preparations) may be dialyzed, without loss of activity, at 2 to 8 °C against 20 mM phosphate buffer, pH 7. The dialyzed preparation is stable at -15 to -25 °C.