Synonyms: (S)-4-((S)-2-phenyl-butyl)-4,5-dihydro-oxazol-2-ylamine
Molecular Formula: C13H18N2O
Molecular Weight: 218.29
Linear Structural Formula: C13H18N2O
MDL Number: MFCD28405494
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present. RO5256390 is a selective TAAR1 agonist shown to be a negative regulator of dopamine transmission. It has antipsychotic activity in models of schizophrenia, reduces cocaine's reinforcng effects, and blocks binge-eating disorder.