Synonyms: 2-chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine hydrochloride (1:1); KRN 568 hydrochloride; NPS-R 568 hydrochloride; Norcalcin hydrochloride; R 568 hydrochloride; Tecalcet hydrochloride
Molecular Formula: C18H22ClNO · HCl
Molecular Weight: 340.29
Linear Structural Formula: C18H22ClNO · HCl
MDL Number: MFCD16038895
Purity: >=95% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: R-568 is a positive allosteric modulator of the calcium-sensing receptor (CaSR), increasing the sensitivity to activation by extracellular Ca2+. In rats, orally administered R-568 decreases plasma levels of PTH and Ca2+ and, at higher doses, increases plasma levels of calcitonin.