Synonyms: Aryl halide chemistry informer library compound X14
Molecular Formula: C12H10FIN4O2
Molecular Weight: 388.14
Linear Structural Formula: C12H10FIN4O2
Melting Point: 195-200 C (w/ decomp.)
Application: This product is Informer compound X14 of the Aryl halide chemistry informer library developed by chemists at Merck & Co., Inc., Kenilworth, NJ, U.S., which contains 18 drug-like molecules representative of those encountered in complex synthesis. By screening a new reaction against the informer library, chemists can directly compare and analyze a reactions's successes and shortcomings among different methods and various research teams. It may also be used to facilitate deeper method development for performance or utility.
Other Notes: Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods, Chem. Sci., 2016, 7, 2604-2613Nanomole-scale high-throughput chemistry for the synthesis of complex moleculesAryl amination using ligand-free Ni(II) salts and photoredox catalysis