Synonyms: 1-(3-Chloro-4-fluorophenyl)-4-[(5-nitro-2-furanyl)methylene]-3,5-pyrazolidinedione
Molecular Formula: C14H7ClFN3O5
Molecular Weight: 351.67
Linear Structural Formula: C14H7ClFN3O5
MDL Number: MFCD01828668
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: PYZD-4409 inhibts ATP-dependent activation of human ubiquitin activating enzyme E1 with an IC50 of 20 mM. PYZD-4409 induces cell death, and inhbits clonogenic growth of leukemia and myeloma cell lines, and inhibits leukemia xenograft tumor growth in mice.