The standard in situ coupling reagent for solid phase peptide synthesis [1-5]. This product can replace BOP in all applications without loss of performance. Unlike uronium-based reagents, PyBOP® does not give rise to guanidinated by-products during cyclization and fragment condensation reactions.The product number for this product was previously 01-62-0016.To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
Synonyms: PyBOP; Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate
Molecular Formula: C18H28N6OP · F6P
Molecular Weight: 520.39
Linear Structural Formula: C18H28N6OP · F6P
MDL Number: MFCD00077411
Purity: >=99.0% (HPLC)
Melting Point: 140-155 C
Legal Information: PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany