PyAOP is a extremely effective coupling which combines the high reactivity of HATU with the lack of side reactions of PyBOP® [1]. It is one of the best coupling reagents for use in cyclization reactions, as it mediates amide bond formation with low racemization and does not cause guanidinylation of free-amino groups.
Synonyms: PyAOP; (7-Azabenzotriazol-1-yloxy)trispyrrolidinophosphonium hexafluorophosphate
Molecular Formula: C17H27F6N7OP2
Molecular Weight: 521.38
Linear Structural Formula: C17H27F6N7OP2
MDL Number: MFCD03703417
Legal Information: PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany