PTAD-Azide (4-(4-(2-Azidoethoxy)phenyl)-1,2,4-triazolidine-3,5-dione) is a 1,2,4-triazolidine-3,5-dione derivative. It can be prepared from ethyl hydrazinecarboxylate.
Synonyms: 4-(4-(2-Azidoethoxy)phenyl)-1,2,4-triazolidine-3,5-dione; N3-Ph-Ur for e-Y-CLICK
Molecular Formula: C10H10N6O3
Molecular Weight: 262.22
Linear Structural Formula: C10H10N6O3
MDL Number: MFCD25976544
Purity: 95%
Storage: 2-8C
Application: PTAD-Azide may be used in the preparation of 4-(4-(2-azidoethoxy)phenyl)-3H-1,2,4-triazole-3,5(4H)-dione and aplaviroc-urazole. This urazole was recently demonstrated in the traceless, chemoselective labeling of peptides and proteins through electrochemical tyrosine-click (e-Y-CLICK) chemistry.
Other Notes: Electrochemically Promoted Tyrosine-Click-Chemistry for Protein Labeling