Propionyl-L-carnitine (PLC), a natural odd-carbon-number, endogenous ester of L-carnitine, is found to be present in humans and animals as a minor component compared to L-carnitine (LC) and acetyl-L-carnitine (ALC). It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo ß-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.
Synonyms: (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt; L-Carnitine propionyl ester; C3-Carnitine; Propanoyl-L-carnitine
Molecular Formula: C10H19NO4
Molecular Weight: 217.26
Linear Structural Formula: C10H19NO4
MDL Number: MFCD00870024
Purity: >=94.0% (HPLC)
Storage: 2-8C
Application: Propionyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography-based techniques. It may also be used as an analytical standard in monitoring the analyte in chemical synthesis procedures and pharmaceutical formulations using a stereospecific enzyme assay and high-performance liquid chromatography technique with UV detection.