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MilliporeSigma

PRIMA-1Met >=98% (HPLC)

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PRIMA-1Met >=98% (HPLC)

Synonyms: 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one; APR-246

Molecular Formula: C10H17NO3

Molecular Weight: 199.25

Linear Structural Formula: C10H17NO3

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: PRIMA-1Met, also called APR-246, is converted to methylene quinuclidinone (MQ), a Michael acceptor. It interacts with p53 through the cysteine (Cys) residue. It blocks the thioredoxin reductase (TrxR1) enzyme. It is under clinical investigation and well-studied. PRIMA-1Met effect is tested on breast cancer specific gene expression.

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Product Detail
Thomas No.
CHM02P306
Mfr. No.
SML1789-5MG
Description
SML1789-5MG, PRIMA-1Met >=98% (HPLC)
CAS Number
5291-32-7
Packaging Size
5 mg
list price/quantitytotal
$0.00
Thomas No.
CHM02P307
Mfr. No.
SML1789-25MG
Description
SML1789-25MG, PRIMA-1Met >=98% (HPLC)
CAS Number
5291-32-7
Packaging Size
25 mg
list price/quantitytotal
$0.00
$0.00 (0 Items)
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