Synonyms: (2S)-2-[[4-[(1RS)-1-[(2,4-diaminopteridin-6-yl)methyl]but-3-ynyl]benzoyl]amino]pentanedioic acid; 10-propargyl-10-deazaaminopterin; N-(4-{1-[(2,4-diaminopteridin-6-yl)methyl]but-3-yn-1-yl}benzoyl)-L-glutamic acid; PDX
Molecular Formula: C23H23N7O5
Molecular Weight: 477.47
Linear Structural Formula: C23H23N7O5
MDL Number: MFCD00920897
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: Pralatrexate is an antifolate that selectively enters cancer cells expressing reduced folate carrier type 1 (RFC-1). Pralatrexate potently inhibits DHFR (dihydrofolate reductase).