Synonyms: 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid trifluoroacetate salt
Molecular Formula: C29H24F3NO2 · C2HF3O2
Molecular Weight: 589.52
Linear Structural Formula: C29H24F3NO2 · C2HF3O2
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: PPTN is a very potent (IC50 = 1 nM) P2Y14 receptor antagonist that does not interact with any other P2Y receptor at concentrations up to 10 muM. PPTN blocks UDP-glucose inhibition of forskolin-induced cAMP accumulation, and neutrophil chemotaxis towards UDP-glucose gradients with nM potency.