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MilliporeSigma

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) PEG Mn 2,000, PLGA Mn 4,000

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Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) PEG Mn 2,000, PLGA Mn 4,000

Synonym: PEG-PLGA, mPEG-b-PLGA

Packaging
1 g in glass bottle

Application
Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Application

  • Good biocompatibility, low immunogenicity and good degradability.
  • Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

    General Description
    Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.

Description: n=45, x=39, y=23 (typical); typical PEG PDI<1.1; overall PDI<1.5 (THF, PEO)

Feed Ratio: lactide:glycolide 50:50

Mol. Wt.: PEG Mn 2,000; PLGA Mn 4,000; average Mn 6,000 (total)

Degradation Timeframe: 1-4 weeks

Transition Temp.: Tm 241-246 °C

PDI: <1.5

Storage Temp.: 2-8°C

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Product Detail
Thomas No.
C970Q24
Mfr. No.
764825-1G
Description
Poly(ethylene glycol) methyl ether-block-poly, 1 g
list price/quantitytotal
$0.00
$0.00 (0 Items)
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