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MilliporeSigma

PKUMDL-WQ-2101 >=98% (HPLC)

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PKUMDL-WQ-2101 >=98% (HPLC)

Synonyms: 2,4-Dihydroxy-benzoic acid 2-[(2-hydroxy-5-nitrophenyl)methylene]hydrazide

Molecular Formula: C14H11N3O6

Molecular Weight: 317.25

Linear Structural Formula: C14H11N3O6

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: PKUMDL-WQ-2101 is a potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) that selectively inhibits serine synthesis in cancer cells. PKUMDL-WQ-2101 binds to allosteric site I, which is located close to active site. PKUMDL-WQ-2101 inhibits tumor growth of MDA-MB-468 xenografts in mice.

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Product Detail
Thomas No.
CHM02L949
Mfr. No.
SML1970-5MG
Description
SML1970-5MG, PKUMDL-WQ-2101 >=98% (HPLC)
CAS Number
304481-72-9
Packaging Size
5 mg
list price/quantitytotal
$0.00
Thomas No.
CHM02L950
Mfr. No.
SML1970-25MG
Description
SML1970-25MG, PKUMDL-WQ-2101 >=98% (HPLC)
CAS Number
304481-72-9
Packaging Size
25 mg
list price/quantitytotal
$0.00
$0.00 (0 Items)
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