Synonyms: 1,3,2-Dioxaborolane, 2-(dichloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Dichloromethyl pinacol boronate
Molecular Formula: C7H13BCl2O2
Molecular Weight: 210.89
Linear Structural Formula: C7H13BCl2O2
MDL Number: MFCD27976342
Purity: >=95%
Density: 1.1423
Refractive Index: n/D 1.4511
Application: Pinacol (dichloromethyl) boronate is a general reagent that was employed by Prof. Greg C. Fu and coworkers to achieve the iterative synthesis of asymmetric (secondary) alkyl boronate esters. These can be further derivatized through a growing suite of chemical transformations developed in the last decade (cross coupling, oxidation, amination, halogenation) that proceed with stereochemical fidelity.
Other Notes: A general, modular method for the catalytic asymmetric synthesis of alkylboronate esters