Phenacetin Melting Point Standard (Phenacetin) is a lipid-soluble drug with moderate solubility with aqueous solvents. Its oral absorption is based on formulation factors like particle size. Its major metabolic route is O-dealkylation to paracetamol and its minor pathways are deacetylation and hydroxylation to form pphenetidine, 2-hydroxyphenetidine, 2- and 3-hydroxyphenacetin and N-hydroxyphenacetin.
Synonyms: Phenacetin; 1-Acetyl-p-phenetidin; 4'-Ethoxyacetanilide; N-(4-Ethoxyphenyl)acetamide; p-Acetophenetidide; Acetophenetidin
Molecular Formula: C10H13NO2
Molecular Weight: 179.22
Linear Structural Formula: CH3CONHC6H4OC2H5
MDL Number: MFCD00009094
Melting Point: 133-136 C (lit.)
Biochem Physiol Actions: Substrate of CYP1A2 and CYP2D6.
Other Notes: USP issued SDS can be found here.