Synonyms: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-2-propenamide
Molecular Formula: C20H14ClFN4O2
Molecular Weight: 396.8
Linear Structural Formula: C20H14ClFN4O2
MDL Number: MFCD28386019
Purity: >=98% (HPLC)
Storage: room temp
Biochem Physiol Actions: PF-6422899 is an alkynylated derivative of PF-6274484; irreversible inhibitor of EGFR kinase activity. PF-6422899 binds covalently to active-site cysteine residues in the ATP binding pocket of EGFR.
Legal Information: Sold for research purposes under agreement from Pfizer Inc.