Synonyms: 3-[[4-[1-(2,2-Difluoroethyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-4-yl]-2-pyrimidinyl]amino]-propanenitrile; PF 04880594
Molecular Formula: C19H16F2N8
Molecular Weight: 394.38
Linear Structural Formula: C19H16F2N8
Purity: >=98% (HPLC)
Storage: room temp
Biochem Physiol Actions: PF-04880594 is a potent and selective RAF inhibitor that inhibits both wild-type and mutant BRAF and CRAF. PF-04880594 potently inhibits tumor growth in BRAF-mutant melanoma xenograft models.
Legal Information: Sold for research purposes under agreement from Pfizer Inc.