Synonyms: Pepsin A; Pepsin from hog stomach
MDL Number: MFCD00081840
Storage: -20C
Application: Pepsin cleavage can be used to produce F(ab′)2 fragments of antibodies. pepsin at www.sigma-aldrich.com/enzymeexplorer.
Biochem Physiol Actions: Preferential cleavage: hydrophobic and aromatic residues in P1 and P1' postitions. Cleaves Phe-Val, Gln-His, Glu-Ala, Ala-Leu, Leu-Tyr, Tyr-Leu, Gly-Phe, Phe-Phe and Phe-Tyr bonds in the beta chain of insulin