Penicillin G also known as benzylpenicillin. It exert a bacteriocidal as well as a bacteriostatic effect on susceptible bacteria by interfering with the final stages of the synthesis of peptidoglycan, a substance in the bacterial cell wall.
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.
Mode of Action: The β-lactam moiety (functional group) of penicillin G binds to the enzyme (DD-transpeptidase) that links the peptidoglycan molecules in bacteria. The enzymes that hydrolyze the peptidoglycan cross-links continue to function, which weakens the cell wall of the bacterium, it causes cytolysis(death due to osmotic pressure) in Bactria.
Antimicrobial spectrum: Gram-positive bacteria.
Grade: Cell culture grade
Potency: >1500 u/mg
Suitability: Suitable for cell culture
Key Applications: Antibiotic
Application Areas: Cell biology
Product Type: Biochemicals
Biochemical Category: Antibiotics
Chemical Class: Antibiotics
Presentation: Powder
Format: Powder
Solubility: Soluble in water (H2O):100 mg/mL.
Sterilization of Solutions: Solutions should be filter sterilized. Store in small aliquots at appropriate temperature until use.
Storage & Handling: Store at +4°C, protect from light