Synonyms: 6-(2,6-Dichlorophenyl)-2-[[3-(hydroxymethyl)phenyl]amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one; PD 166326
Molecular Formula: C21H16Cl2N4O2
Molecular Weight: 427.28
Linear Structural Formula: C21H16Cl2N4O2
Purity: >=98% (HPLC)
Storage: room temp
Biochem Physiol Actions: PD166326 is an ATP-competitive dual BCR-ABL and Src kinase inhibitor. In some studies it has been found to be more potent than imatinib with inhibition of cancer growth in the low nanomolar range or even picomolar range in various biological systems.
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