Antigen: synthetic peptide from human PCSK9 amino acids 490-502
Host: rabbit
Cross Reactivity: (+) human, murine, and rat PCSK9
Application(s): ICC and WB
PCSK9 is a member of the subtilisin serine protease family with an important role in lipoprotein metabolism. Several gain of function mutations in the PCSK9 gene are associated with hypercholesterolemia which is characterized by an increase in LDL cholesterol levels.