Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.
Synonyms: FNDC5 (cleaved); Poly(ADP-ribose) glycohydrolase
Purity: >95% (SDS-PAGE)
Storage: -70C
Other Notes: Human PARG is fused to a His-tag.