Oligomycin is a natural antibiotic isolated from Streptomyces diastatochromogenes, which is a mixture of oligomycins A, B, and C.
Oligomycin is used as antibiotic which inhibits respiration in mitochondria. It inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production).
It inhibits mitochondrial ATPase and phosphoryl group transfer.
Key Applications: Antibiotic
Product Type: Biochemicals
Biochemical Category: Pharmaceuticals
Chemical Class: Pharmaceuticals
Melting Point: 150°C(Lit.)
Presentation: White Powder
Format: Powder
Formulation: A mixture of oligomycin A, B and C in an approximate ratio of 60:30:10 Oligomycin A: C45H74O11 Oligomycin B: C45H72O12 Oligomycin C: C45H74O10
Solubility: Soluble in ether, benzene, absolute ethanol, glacial acetic acid and acetone. Storage & Handling: Store at +4°C.