NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
- Totally spherical particle shape
- Outstanding surface microstructure
- High pressure stability
- Low metal content
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® C18 Isis
Nonpolar crosslinked polymeric octadecyl modification, endcapped, USP L1
Key features:
- Exceptional steric selectivity
- Outstanding surface deactivation
- Suitable for LC/MS and HPLC at pH extremes (pH 1–10)
Technical characteristics:
- C18 phase with special polymeric, crosslinked surface modification
- Pore size 110 Å
- Particle sizes 1.8 μm (UHPLC), 3 μm and 5 μm
- Carbon content 20 %
Recommended application: Steroids, (o,p,m-) substituted aromatics, fat-soluble vitamins