Synonyms: 2-Hydroxy-benzoic acid (2E)-2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
Molecular Formula: C18H14N2O3
Molecular Weight: 306.32
Linear Structural Formula: C18H14N2O3
MDL Number: MFCD00196698
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: NSAH is a cell penetrant, potent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase). NSAH binds to catalytic site of hRRM1. It inhibits hRR in cells. NSAH exhibit potent cytotoxicity toward cancer cells, while demonstrated very moderate toxicity against normal blood progenitor cells.