NOS Inhibitor Kit

This kit contains four nitric oxide synthase (NOS) inhibitors: 7-NI, L-NMMA, L-NIL, and L-NIO. 7-NI is a selective inhibitor for the brain nitric oxide synthase (NOS).

• Yellow orange solid soluble in DMSO
• Store desiccated at 4°C
• C₇H₅N₃O₂
• MW: 163.1
• [2942-42-9]

L-NMMA (N^G-Methyl-L-arginine, acetate salt) competitively inhibits nitric oxide synthase in a wide range of cells.

• White solid soluble in water
• Store desiccated at 4°C
• C₉H₂₀N₄O₄
• MW: 248.3
• [53308-83-1]

L-NIL (N⁶-(1-Iminoethyl)-lysine, hydrochloride) is a potent and selective inhibitor of nitric oxide synthase that exhibits about 28-fold greater selectivity for inducible nitric oxide synthase (IC₅₀ = 3.3 uM) than for the rat brain constitutive enzyme (IC₅₀ = 92 uM). It exhibits about 10-fold greater inhibitory potency than NG-monomethyl-L-arginine in inhibiting γ-interferon-induced NO₂€“ production (IC₅₀ = 460 nM).

• White solid soluble in water
• Store at 4°C
• C₈H₁₉Cl₂N₃O₂
• MW: 260.2
• [150403-89-7]

L-NIO (N⁵-(1-Iminoethyl)-L-ornithine, dihydrochloride) is a potent, irreversible inhibitor of neutrophil nitric oxide synthase.

• White solid soluble in water
• Store desiccated at -20°C
• C₇H₁₇Cl₂N₃O₂
• MW: 246.1
• [36889-13-1]