Antigen: human recombinant Nod2 amino acids 28-301
Host: mouse, clone 2D9
Cross Reactivity: (+) human Nod2
Application(s): IHC and WB
Nod2 is a member of the apoptosis regulating protein family that has caspase recruitment-domains (CARDs) and also includes Apaf-1 and Nod1. Nod1 and Nod2 act as intracellular receptors for bacterial lipopolysaccharides, activate NF-κB, and contribute to inflammatory bowel disease.