Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Tyr1336 of the human NMDA Receptor NR2B Subunit
Host: rabbit
Cross Reactivity: (+) human and rat NMDA receptor; expected to react with bovine, canine, chicken, mouse, non-human primates, and zebrafish NMDA receptor
Application(s): WB
Phosphorylation of Tyr1336 in NR2B is thought to potentiate NMDA receptor-dependent influx of calcium. Ischemia may also increase the phosphorylation of this site.