CAS Number 55981-09-4
Empirical Formula (Hill Notation) C12H9N3O5S
Molecular Weight 307.28
EC Number 259-931-8
MDL number MFCD00416599
assay =98% (HPLC)
storage temp. 2-8°C
Biochem/physiol Actions
Nitazoxanide is an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR); Antimicrobial recently found to kill both non-replicating and replicating mycobacteria. FDA approved anti-parasitic drug (2002). Recent work (C & EN Sept. 14, 2009, p. 28) highlights that NTZ kills non-replicating and replicating TB bacteria and no apparent resistance is detected.