Synonyms: 4-(2-(5-Nitro-1H-imidazol-1-yl)ethyl)morpholine; K 1900; K-1900; K1900; NSC 107524; NSC-107524; NSC107524
Molecular Formula: C9H14N4O3
Molecular Weight: 226.23
Linear Structural Formula: C9H14N4O3
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: Nimorazole is a nitroimidazole-based hypoxic cell-radiation sensitizer with less toxicity than etanidazole or misonidazole. Under low oxygen (hypoxic) condition, reductive activation of its 5-nitroimidazole moiety leads to enhanced adduct formation with reduced glutathione, which form the basis of cancer/tumour-selective radiation sensitization. Nimorazole is also a known anti-infective agent against trichomoniasis, an infectious disease caused by the protozoan parasite Trichomonas vaginalis.