Synonyms: 5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)-benzamide; ML414
Molecular Formula: C17H22N4O3S2
Molecular Weight: 394.51
Linear Structural Formula: C17H22N4O3S2
Purity: >=95% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation. NGI-1 inhibits the oligosaccharyltransferase, preventing the attachment to the protein. NGI-1 has been shown to induce senescence in receptor tyrosine kinase dependent tumors.