Antigen: human NF-κB (p65) amino acids 526-539
Host: mouse, clone 112A1021
Isotype: IgG1κ
Cross-Reactivity: (+) human, mouse, and rat NF-κB (p65); expected to react with bovine, gorilla, monkey, and porcine NF-kB (p65)
Application(s): FC, IHC, and WB
The active nuclear form of the NF-κB transcription factor complex is composed of two DNA binding subunits, NF-κB p65 and p50. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65.