Synonyms: 2-amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine; 506U; 506U78; 9-beta-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine; Arranon; Atriance; GW-506U78
Molecular Formula: C11H15N5O5
Molecular Weight: 297.27
Linear Structural Formula: C11H15N5O5
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: Nelarabine is an antineoplastic purine nucleoside analog used in T-cell acute lymphoblastic leukemia. It is a pro-drug of Ara-G, which is converted by cellular kinases to the active 5'-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis.