Synonyms: 1H-Imidazole (OC-6-11)-tetrachloro(1H-imidazole-kappaN3)[1,1'-(sulfinyl-kappaS)bis[methane]]ruthenate(1-) (1:1); ImH[trans-RuCl4(DMSO)Im]; Imidazolium trans-imidazoledimethyl sulfoxide-tetrachlororuthenate
Molecular Formula: C5H10Cl4N2ORuS · C3H5N2
Molecular Weight: 458.18
Linear Structural Formula: C5H10Cl4N2ORuS · C3H5N2
Purity: >=98% ruthenium (Ru) basis (elemental analysis)
Storage: -20C
Biochem Physiol Actions: NAMI-A is a potent antimetastatic drug in vivo that is exhibits little cytotoxicity towards many cancer cell lines. Antimetastatic of NAMI-A is attributed to the formation of adducts with membrane and cytosolic proteins. Nevertheless NAMI-A induces potent and selective cytotoxic effects in several leukemia cell lines. NAMI-A exhibits low toxicity for host tissues.