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MilliporeSigma

N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt =96% (HPLC), powder

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N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt =96% (HPLC), powder

Synonym: Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt
CAS Number 16980-89-5
Linear Formula C18H23N5O8PNa
Molecular Weight 491.37
EC Number 241-059-4
MDL number MFCD00005843
PubChem Substance ID 24893246

Biochem/physiol Actions
Cell-permeable cAMP analog that activates cAMP dependent protein kinase (PKA).

Caution
Loses 2'-O-butyryl group at pH 8.5

Application
Dibutyryl cAMP is a cell-permeable cAMP analogue that activates cAMP dependent protein kinase (PKA) or the cAMP/PKA signaling pathway. Dibutyryl cAMP is used as a morphological differentiation inducer and cell signaling modulator in cells such as Schwann cells. It is used in a variety of neural differentiation studies.

assay  =96% (HPLC)
form  powder
impurities  =0.5% Cyclic AMP
 =3% monobutyryl derivatives
color  off-white
solubility  H2O: soluble50 mg/mL
storage temp.  -20°C

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Thomas No.
C974R79
Mfr. No.
D0627-250MG
Description
N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt =96% (HPLC), powder, 250MG
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