Synonyms: (N6pATP) sodium salt; N6-Propargyl-adenosine-5'-triphosphate sodium salt
Molecular Formula: C13H18N5O13P3 · xNa+
Linear Structural Formula: C13H18N5O13P3 · xNa+
Purity: >=95% (HPLC)
Storage: -20C
Application: N6-Propargyl-ATP is suitable for in vitro AMPylation of proteins as well as in vitro polyadenylation of RNA. The resulting alkyne-functionalized protein or RNA can be processed using Cu(I)-catalyzed click chemistry to attach azide-labeled molecules. This gives options such as introduction of a biotin group for purification tasks, introduction of a fluorescent group for detection, or crosslinking to other azide-functionalized biomolecules.
Legal Information: The purchase of this product for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry ("Click Chemistry") includes a limited, nontransferable license to intellectual property owned by The Scripps Research Institute to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals and manufacturing purposes. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or [email protected].