Synonym: 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt hydrate
Empirical Formula (Hill Notation): C35H35ClNO3S·Na · xH2O
Molecular Weight: 608.17 (anhydrous basis)
MDL Number: MFCD20527317
Biochem/physiol Actions
Montelukast sodium hydrate is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. It is a subtype specific CysLT1 receptor antagonist.
Assay: =98% (HPLC)
Form: powder
Optical Activity: [a]/D +90 to +106° in methanol (c=1)
Storage Condition: desiccated
Color: white to tan
Solubility: DMSO: =8 mg/mL at 60 °C
Storage Temp.: 2-8°C