MDL No.: MFCD00145922
Storage: -20C
UNSPSC Code: 12352203
General description: Vimentin is a 53 kD type III intermediate filaments expressed in breast myoepithelial cells, osteocytes, langerhans cells of the skin, schwann cells and astrocytes. It has a crucial role in motility, maintenance of cell shape and endurance of mechanical stress of mesenchymal cells. Monoclonal anti-vimentin antibody can be used in immunofluorescent labeling of frozen tissue sections to localize vimentin in fibroblasts, endothelial cells, lymphoid tissues and melanocytes. It can also be used in western blotting. Mouse anti-vimentin antibody reacts specifically with vimentin. This product has also shown best reactivity with cultured chicken fibroblasts and can also react with human and mouse cells or tissues.
Application: Monoclonal anti-vimentin antibody can be used in immunocytochemical localization of vimentin in normal and pathological tissue of mesenchymal origin. It can also be used in immunoblotting and indirect immunofluorescence (1:200). Further, anti-vimentin antibody can be used to distinguish tumors and metastatic lesions derived from sarcomas, lymphomas, and melanomas.
Immunogen: human foreskin fibroblasts
RIDADR: NONH for all modes of transport
WGK Germany: 3