Synonyms: CAKB; FAK2; FRNK; PKB; PTK
Storage: -20C
UNSPSC Code: 12352203
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General description: Protein tyrosine kinase 2 +¦ (PTK2B) is a member of the focal adhesion kinase family which is expressed in the brain. The gene encoding it is localized on human chromosome 8.
Biochem/physiol Actions: Protein tyrosine kinase 2 +¦ (PTK2B) takes part in the +¦2-mediated signaling pathway and activates mitogen activated protein kinase pathway. The protein has been shown to be upregulated in many tumors. PTK2B also has a role in cell proliferation and migration. It regulates ion channels which are induced by calcium.
Immunogen: Purified recombinant fragment of PYK2 (aa815-997) expressed in E.coli.Mouse monoclonal antibody raised against PYK2
Physical form: Ascitic fluid containing 0.03% sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: 3