Monoclonal Anti-MeCP2 (mouse IgG1 isotype) is derived from the Men-8 hybridoma produced by the fusion of mouse myeloma cells (NS1) and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to the N-terminus of human MeCP2.
MDL Number: MFCD02686372
Storage: -20C
Application: Monoclonal Anti-MeCP2 antibody has been used:
•in western blotting
•in immunoblotting
•in flow cytometry
•in immunohistofluorescence
•in immunocytochemistry
Biochem Physiol Actions: Methyl-CpG binding protein 2 (MeCP2) has been shown be crucial for brain development. It part of the methyl-CpG-binding proteins, which are involved in repression of gene expression by binding to methylated DNA. Mutations in the gene encoding MeCP2 have been associated with Rett syndrome (RTT).