Synonyms: AGS; AHD; AWS; CD339; HJ1; JAGL1; MGC104644
Storage: -20C
UNSPSC Code: 12352203
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General description: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. (provided by RefSeq)
Immunogen: JAG1 (NP_000205, 905 a.a. ~ 1014 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHV
Physical form: Solution in phosphate buffered saline, pH 7.4
RIDADR: NONH for all modes of transport
WGK Germany: 3