Synonyms: Anti-BUB1beta; Anti-BUBR1; Anti-Bub1A; Anti-MAD3L; Anti-SSK1; Anti-hBUBR1
MDL No.: MFCD04040371
Storage: -20C
UNSPSC Code: 12352203
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General description: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. (provided by RefSeq)
Immunogen: BUB1B (AAH18739, 1 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceMAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGALAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDPRFLNLWLKLGR
Physical form: Solution in phosphate buffered saline, pH 7.4
RIDADR: NONH for all modes of transport