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MilliporeSigma

MMP-2/MMP-7 Substrate, Fluorogenic

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Extremely sensitive fluorogenic substrate for matrix metalloproteinases (MMPs). Suitable for assessment of total activity in crude preparations by continuous assays (kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M-1sec-1 for MMP-2).

Peptide SequenceMCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 ·TFA [Dpa = N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]
FormYellow solid
FormulationSupplied as a trifluoroacetate salt.
Primary TargetFluorogenic substrate for matrix metalloproteinases (MMPs)
Primary Target IC50kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M-¹ sec-¹ for MMP-2
Molar mass1093.1
Protect from MoistureYes
Purity≥95% by HPLC
Excitation max.~325 nm
Emission max.~393 nm
Solubility20% Acetic Acid
Chemical formulaC49H68N14O15
Storage-20°C
ShipAmbient Temperature Only
Standard Handling

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Product Detail
Thomas No.
C974Y57
Mfr. No.
03-32-5032-1MG
Description
MMP-2/MMP-7 Substrate, Fluorogenic, 1MG
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