Synonyms: 2-(4-Methylphenylsulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide; 2-[[(4-Methylphenyl)sulfonyl]amino]-N-(4-phenyl-2-thiazolyl)-4-(trifluoromethyl)-benzamide
Molecular Formula: C24H18F3N3O3S2
Molecular Weight: 517.54
Linear Structural Formula: C24H18F3N3O3S2
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: ML364 is a potent and specific inhibitor of the deubiquitinase USP2 that induces cellular Cyclin D1 degradation in HCT116 colorectal cancer cells, followed by cell cycle arrest and apoptosis. Also, ML364 inhibits homologous recombination (HR)-mediated DNA repair.