Synonyms: N-[2-(Cyclopentylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-1H-benzimidazole-1-acetamide hydrochloride
Molecular Formula: C29H29FN4O2 · HCl
Molecular Weight: 521.03
Linear Structural Formula: C29H29FN4O2 · HCl
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: ML309 is a potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) (R132H and R132C) that binds reversibly the enzyme. ML309 inhibits production of neomorphic 2-hydroxyglutarate in glioblastoma cell line.